Gene Synthesis Market - Global Size, Share, Trends, Growth and Forecast Year ( 2022 – 2032 )

Gene Synthesis Market Dynamics

Gene Synthesis Market By Method ( Solid-phase synthesis, Chip- based synthesis, PCR- based Enzyme synthesis, Others) Service (Antibody DNA synthesis, Viral DNA synthesis, Others) Application( Gene & cell therapy development, Vaccine development, Diseases diagnosis, Others) End Users( Biotechnology & pharmaceutical companies, Academic & government research institutes, Contract research organizations) and Geographic Regions (North America, Europe, Asia Pacific, Latin America, Middle East and Africa): Industry Trends and Global Forecasts, 2023-2032

Market Size and Overview:

The gene synthesis market has experienced substantial growth, with a compound annual growth rate (CAGR) of 18.7% from 2023 to 2032, reaching a market value of $11.3 billion in 2032. This growth can be attributed to the increasing demand for synthetic genes in various applications, including pharmaceutical research, biotechnology, and agriculture. Gene synthesis plays a vital role in genetic engineering, drug discovery, and personalized medicine. The market comprises a wide range of gene synthesis services and products, such as gene fragments, genes of interest, and gene libraries. The market is highly competitive, with key players continuously innovating to meet the evolving needs of researchers and industry professionals.

Market Segmentation:

Method:

• Solid-phase Synthesis
• Chip-based Synthesis
• PCR-based Enzyme Synthesis
• Others

Services:

• Antibody DNA Synthesis
• Viral DNA Synthesis
• Others

Applications:

• Gene & Cell Therapy Development
• Vaccine Development
• Disease Diagnosis
• Others

End-Users:

• Biotechnology & Pharmaceutical Companies
• Academic & Government Research Institutes
• Contract Research Organizations (CROs)

Geographic Regions:

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East and Africa

Solid-phase Synthesis: The solid-phase synthesis segment holds the largest market share in the gene synthesis market. This method has witnessed increasing adoption in recent years due to its versatility and ability to create modified and canonical nucleic acid polymers such as RNA or DNA. Solid-phase synthesis accounted for highest of the revenue share in 2022, making it a prominent technology for various research purposes and applications across different fields.

Gene & Cell Therapy Development: The gene & cell therapy development segment dominates the gene synthesis market, capturing highest of the revenue share in 2022. This segment is expected to drive the advanced therapies pipeline for the treatment of chronic diseases. Gene and cell therapies are gaining significant acceptance among therapy developers due to their effectiveness in treating diseases that were previously untreatable through traditional treatment methods.

Regional Analysis:

The regional analysis of the gene synthesis market reveals diverse trends and dynamics across different parts of the world. Starting with North America, this region boasts one of the largest and most mature markets, primarily driven by the presence of major pharmaceutical and biotechnology companies, robust research infrastructure, and government support for genetic research. In Europe, countries like Germany, France, and the United Kingdom hold significant market shares in the gene synthesis market. The region showcases a strong academic and research environment, fostering innovation in genetic research and synthetic biology. Moving to the Asia Pacific region, it is projected to witness the fastest growth rate during the forecast period. This growth can be attributed to increasing research activities for the development of effective therapeutics and a growing interest in synthetic biology research. Lifestyle changes have led to a rising incidence of diseases, driving the demand for innovative solutions. Latin America demonstrates steady growth in the gene synthesis market, fueled by urban development, a rising middle class, and a growing demand for advanced healthcare services. Brazil, Mexico, and Argentina are key markets within the region, experiencing increased adoption of gene synthesis technologies and services. The Middle East and Africa exhibit a developing market with a focus on urban development, tourism, and an increasing emphasis on healthcare advancements. The United Arab Emirates, Saudi Arabia, and South Africa are notable contributors to the market's growth in this region.

Growth Drivers:

The increasing demand for customized genetic material in various research and commercial applications propels the market. Gene synthesis allows researchers to design and produce genes with specific sequences and functions, enabling advancements in fields such as drug discovery, genetic engineering, and agricultural biotechnology.

The prevalence of chronic disorders is on the rise, driven by changing lifestyles and an aging population. Gene synthesis plays a crucial role in studying and addressing these disorders, such as oncology, cardiovascular diseases, HIV, and gastrointestinal disorders.

Additionally, the growing adoption of gene synthesis in pharmaceutical research and development contributes to market growth. The ability to synthesize genes that encode therapeutic proteins, antibodies, and viral vectors for gene therapy has opened new avenues for drug discovery and personalized medicine. The continuous advancements in DNA synthesis technologies and reduced costs have further accelerated the adoption of gene synthesis in the pharmaceutical industry.

Moreover, the rising prominence of synthetic biology and its applications in various industries, including healthcare, agriculture, and industrial biotechnology, drive the demand for gene synthesis. Synthetic biology aims to engineer biological systems using genetic components and synthetic genes, leading to the development of novel products and solutions.

The increasing emphasis on clinical research and the development of personalized medicine has created a strong demand for gene synthesis. Researchers and healthcare professionals are utilizing gene synthesis to study and understand the genetic basis of diseases, leading to the development of targeted therapies and personalized treatment approaches.

Challenges:

The high cost of treatment for chronic disorders, especially in advanced gene therapies, can limit market adoption. Additionally, the rapid advancements in gene therapy require skilled professionals for gene insertion procedures, which may pose a challenge due to a lack of skilled individuals

Key Companies:

The gene synthesis market is driven by several leading companies that have established themselves as key players in the industry. These companies possess a strong market presence, extensive distribution networks, and a diverse product portfolio. They employ competitive strategies such as product innovation, strategic partnerships, mergers, and acquisitions to enhance their market share and cater to the varied needs of customers. Some of the prominent companies in the gene synthesis market include GenScript, GENEWIZ, Boster Biological Technology, Twist Bioscience, ProteoGenix, Inc., Biomatik, ProMab Biotechnologies, Inc., Thermo Fisher Scientific, Inc., Integrated DNA Technologies, Inc., and OriGene Technologies, Inc. Among other players.

These companies have showcased their commitment to innovation and advancement in gene synthesis technology through various product launches. For instance, in July 2022, OraSure Technologies introduced OmniGene, a state-of-the-art gut DNA and RNA product that offers enhanced performance and reliability.

Additionally, in April 2022, DNA Script, a customer of the syntax system, introduced a cutting-edge DNA synthesis technique through an early program, demonstrating their dedication to advancing the field of gene synthesis.